Firstly, I am back after a month-long hiatus. Sorry about that.

Secondly, and this may be specific to my system, Ojo Bueno causes massive performance issues to my game. Specifically, when the Nuka Cola machine is retextured by Ojo Bueno, and remember, just Ojo Bueno, New Vegas with TTW installed can go from 60 FPS to around 21 or 16 FPS. I don't mind not using the pack, but I really like the roads and the enhanced textures that come with it. Any reason as to why this happens, and possibly a fix anywhere?

There are several different texture options if you're having those kind of issues. I did as well on my old rig so I used the performance pack (up to 2k textures) and eventually went to the vanilla pack after adding more textures elsewhere. I found even the vanilla pack was very good work so I stuck with it.

Your issue is likely caused by the esp provided with the Nuka Machine re texture. It makes it fully destructible, but unfortunately causes huge lag/ fps drogs. Just delete the esp. Or, if using mod organizer, double click ojo beuno in the left pane, go to optional esp, select the esp, then click the up arrow to hide it. Should fix the issue.

Oh i've been having issues too, ill try out the vanilla pack and delete the esp

Gracias to you guys for posting and giving me some fixes. I'll test these out and report back in a bit.

How about trying Poco Bueno, the scaled down version of Ojo?