For some reason after a few minutes of game play my textures begin to flash and then show up in many psychedelic colors. Not sure what is causing it but I'd sure like to find out. Once I reload the game I'm fine for another short while.
I also have a problem in that after a few restarts the FO4 menu comes up and when I select play the same screen restarts in an infinite loop requiring a full restart of my PC and then Steam for me to get the game going again.