Well, I'm no expert but using Wyre Bash method provides a lot of options when creating the bash patch all the way down to setting timescale, naming conflicts, etc. I believe it's only for FNV, Skryim. Unless you know what you are doing performing a Merged patch via FNVEdit consist of loading all mods or selected mods, choosing the last ESP in the load order, right clicking and selecting Merge. Any additional tweaks you have to perform manually. Not to take the above literally but just a quick informative summary.