What weapons do you use guys ?
Personaly I use :

-USP 45 match
-HK 416 17"
-HK G36K 9"
-Tactical m1911A1/Desert eagle 50
-Browning 20mm/Minigun 161
-Artillery flares/Liberty Nuka grenades
-AK 103 whatever size
-HK 417 20" sniper sd
-USAS 12

Mk 14 EBR - Designated Marksman Setup + Silencer
---Main Carry with 20 mags that is 600 .308 bullets

MK-14 EBR:

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Colt 1911 - Upgraded pistol + Silencer
---Secondary Carry with 4 mags that is 32 .45 bullets

Colt 1911:

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Stealth Combat Knife - Combat Knife + Stealth Upgrade
---Tertiary Carry/Close Encounters

Combat Knife:

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I like to keep a realistic carry at all times. Practice restraint with ammo and weight coordination, as well as playing the game in Survival to balance things out and not make the game more of a mockery than it already is.

If I count correctly and my estimations are correct, along with the armor, clothing, gear, weaponry and ammo my character is carrying that should all round up to 40-50kgs or 88-110lbs.

@NOVA

Thks to have added screenshots man.
I don't because I am at work and post with my phone the most of my time, but great you did it

- Ka Bar BK-9 knife
- M1911 pistol
- Sten Mk. II submachine gun
- AK-47 automatic rifle
- DKS-501 sniper rifle
- Fragmentation grenades

And that is my lot. I try to switch weapons based on enemies. Knife for roaches and moles, while the pistol is fine for ghouls, when the yao-guais comes charging I use the submachine gun, and mutants tend to make me get the AK out. I use the sniper for all of the above if I see them before they see me.

Usually I'd also pack a shotgun of some kind for the punch, but I'm not a fan of the vanilla ones.

When playing Fallout 4 im normally rocking:

NAVI Power armor - love that its so different ( looks like what the Japanese would come up for power armor during the great war)
CROSS PlasRail - Multiple roles available normally used in shotgun configuration and reflex sight
DKS-501 Sniper rifle - For long range engagements, a Fallout classic returns!
Falcon III Scout pistol - For when I have to ditch the PA and go quietly
melee is underwhelming in FO4 so I avoid it as much as possible
Frag grenades currently carried until someone makes a microfusion cell grenade like in GRA from FNV

Very unrealistic loadout but ive played through the game at minimum 10 times... I dont care anymore lol.

-Wasteland Melody's Chinese Assault Rifle
-Silenced Mauser C96
-Plasma Crossbow (for sniping at medium range)
-Gewher98 scoped (for those long distance snipes.)
-GUN's very own Chinese Stealth Suit.

It's a carry-over from a previous character.

Spoiler:

I usually run around with a 5.56x45mm whatever from modern firearms usually SCAR-L or HK416
This play through is a FDE HK416 12" , Colt 1911A1 and Mk14 EBR with Eclan 4x sight with frags as my explosive.

Depends on what kind of character I'm playing, but here was my first run through loadout without mods (vanilla):
-.44 Snubnose
-Hunting Rifle
-Grenades

Aaaand with mods:
-MK14 EBR
-Colt 1911
-Grenades

Its interesting to see what others use for weapons during a run though.

My girl likes up close and personal so I am using Catalyst AAS Shotgun now, or Desert Eagle pistol most of the time but do always carry the MK-14 as never know when you need some punch.

I like to roll with my scoped lever action for longer range, my defense gun for medium, and of course, the deliverer, for when shit just needs to die.

I play a terminator so a lever action shotgun for close range, as a handgun I run a 1911a1, for medium range or if I'm low on ammo and as a melee I rip peoples arms off with my bare hands and beat them to death with them.

10mm pistol
45-70 carbine
if in power armor-
Flamer
Laser rifle

Now in a the development of new sub-machine gun (L CAR-9). Done 20%  

Spoiler:

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Currently, this mod is ready to 99%, it remains to be translated into English:

HS 2000:

On this playthrough:

-M1911 A1
-DSR-1
-M4 with magpul grip and stock and an aimpoint
-Lever action rifle
-CROSS plasmarail
-1858 remington revolver
-plasma crossbow
-M1014

I typically carry quite a large arsenal, but end up only using some of it.

-Kellog's Pistol (Renamed 'Reminder' and upgraded) is my main sidearm, as it packs enough punch to take down standard enemies in a couple of shots.
-A Plasma Pistol for when the above won't quite cut it, or is low on ammo.
-'The Last Minute' Gauss Rifle for when I run into anything too big for smaller arms.

I also carry a sack full (usually up towards 60) Relay Grenades rather than an assault/automatic weapon to thin out bands of raiders and ghouls for easy mop up. I love standing back and watching my minions handle the lesser battles for me. After all, what's the point of (almost) limitless resources and an army of kill-bots if you lower yourself to fighting simple bandits and mutants?